The main focus of the video was to explore different aspects of photography and highlight its ability to connect with people on a deeper level beyond just visual representation. It emphasized that photography is not just about capturing images, but also about capturing moments, emotions, and various other elements. The video emphasized that photography is more than just pictures. One quote from the TED talk stated that to be a great photojournalist, it is important to consistently produce great photographs and also know how to create a visual narrative and tell a story.